The Effect of Arsenic on some Antioxidant Enzyme Activities and Lıpıd Peroxidatıon in Various Tissues of Mirror Carp Cyprinus Carpio Carpio

Altıkat S. , Uysal K., Kuru H. İ. , Kavasoğlu M., Öztürk G. N.

İCWEE 13 (the second international conferance on water energy environment.), Aydın, Turkey, 21 - 24 September 2013, pp.66-67 identifier identifier identifier

  • Publication Type: Conference Paper / Summary Text
  • Doi Number: 10.1007/s11356-014-2896-6
  • City: Aydın
  • Country: Turkey
  • Page Numbers: pp.66-67

Abstract

The effect of arsenic bioaccumulation in liver, kidney, intestinal, muscle and skin tissues of mirror carp (Cyprinus carpio carpio) was investigated on lipid peroxidation and certain antioxidant enzyme activities. In this study 3 aquarium groups were formed from mirror carp: control group, 0.5 mg/L and 1 mg/L arsenic concentrations. The fish were dissected after 1 month. Arsenic bioaccumulation, malondialdehyde (MDA) levels, catalase (CAT) and superoxide dismutase (SOD) enzyme activities were determined in the tissues. Results showed that arsenic was accumulated in liver, kidney, intestinal, skin and muscle tissues. As the final product of lipid peroxidation, MDA levels were observed to have increased in all tissues with the exception of muscle. On the other hand, CAT and SOD enzyme activities in the fish tissues were decreased as compared to the control group. In the muscle tissue, differences were observed in the enzyme activities depending on arsenic concentration. Considering the increases in enzyme inhibition and MDA levels, liver was observed to be the main tissue affected in response to the arsenic toxicity.