Molecular and biochemical evidence on the protective effects of embelin and carnosic acid in isoproterenol-induced acute myocardial injury in rats
LIFE SCIENCES, vol.147, pp.15-23, 2016 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 147
- Publication Date: 2016
- Doi Number: 10.1016/j.lfs.2016.01.038
- Journal Name: LIFE SCIENCES
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.15-23
- Keywords: Carnosic acid, Embelin, Heart, Isoproterenol, Myocardial infarction, Myocardial ischemia, ISCHEMIA-REPERFUSION INJURY, DECREASES CARDIOMYOCYTE APOPTOSIS, CULTURED CARDIAC MYOCYTES, OXIDATIVE STRESS, INDUCED CARDIOTOXICITY, ANTIOXIDANT RESPONSE, BINDING PROTEIN, TROPONIN-I, DAMAGE, HEART
- Kütahya Health Sciences University Affiliated: Yes
Abstract
Aims: Acute myocardial infarction is a serious acute cardiac disorder and heart disease is still a major public health problem in adults. We investigated the effects of embelin (EMB) and carnosic acid (CA) in animals with isoproterenol (ISO)-induced myocardial injury.