Background: The utilization of information technologies in healthcare is gradually increasing. However, more studies need to examine how these technologies impact service quality and privacy perception. Aim: This research aims to elucidate the relationship between health information exchange, information security, privacy, and service quality from the user's perspective. Methods: The data were collected between February and May 2019 through a structured questionnaire and face-to-face interviews. The study included 416 participants (250 women, 165 men; average age: 34.46±12.64) who received health care from independent pharmacies. Data were analyzed using the CHAID algorithm in the R Program. Results: By employing the CHAID algorithm, two primary groups emerged: The first group believes that health information technologies enhance service quality and provide support. However, the second group holds a negative attitude toward the impact of information technologies on service quality. In the branch-leaf relationship of the first group, it is indicated that health information technologies do not harm patient privacy, and the participants are knowledgeable about electronic health records. However, in the branch-leaf relationship of the second group with a negative attitude, the statements emphasize that the participants are aware of health information technologies and perceive these technologies as affecting privacy. Discussion and Conclusion: Familiarity with health information technologies and electronic health records significantly influences privacy concerns. Consequently, it would be appropriate to implement policies and strategies tailored to the specific target groups to enhance the perception of healthcare quality among users.