The predictive value of computerized tomography‐assessed sarcopenia for complicated appendicitis in geriatric patients


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Yıldırım A. C., Atlanoğlu Ş., Gedik M. A., Zeren S., Ekici M. F.

Aging Medicine, vol.6, no.3, pp.1-8, 2023 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 3
  • Publication Date: 2023
  • Doi Number: 10.1002/agm2.12259
  • Journal Name: Aging Medicine
  • Journal Indexes: Scopus
  • Page Numbers: pp.1-8
  • Kütahya Health Sciences University Affiliated: Yes

Abstract

Objective: Geriatric patients have more complicated appendicitis, which leads to higher morbidity and mortality rates. Sarcopenia has been shown to have a negative impact on patients undergoing surgery. This study aims to reveal the predictive value of computerized tomography-assessed (CT-assessed) sarcopenia for complicated appendicitis in geriatric patients. Methods: One-hundred fifty-four patients’ with acute appendicitis age, gender, co- morbidities, appendicitis status, and body mass index (BMI) values were analyzed. The skeletal muscle index (SMI) and related measurements were evaluated. Results: Fifty-two percent of the patients had complicated, and 48% had uncompli- cated appendicitis. There was a statistically significant difference between uncomplicated and complicated cases regarding BMI, SMI, and muscle area values (P < 0.05). The cutoff point by Receiver Operating Characteristic Curve analysis was conducted for SMI and showed 71% sensitivity and 52% specificity (P = 0.042). Multivariate analysis has shown that comorbidities are significantly more associated with complicated appendicitis than sarcopenia. Conclusion: Geriatric patients with lower BMI, decreased muscle area, and CT-detected sarcopenia have an increased risk of complicated appendicitis. Comorbidities are also important risk factors. Surgeons should be aware of factors leading to complicated appendicitis, which may cause higher morbidity and mortality rates in elderly patients.