The effect of oxidized cellulose use on postoperative hypocalcemia development in thyroid surgery

Ekici M. F., Zeren S., Yıldırım A. C., Yaylak F., Arık Ö., Deveci U., ...More

KSÜ Tıp Fakültesi Dergisi, vol.16, no.2, pp.1-10, 2021 (Peer-Reviewed Journal)


BACKGROUND Hypocalcemia is a frequent complication in patients after thyroid surgery. Especially permanent hypocalcemia is the most common complication and it can cause significant morbidity. Also postoperative haemorhage is uncommon life-threatening complication of thyroid surgery. In this study we compare calcium metabolism and complications between oxidized regenerated cellulose gauze (OC) + conventional haemostasis versus conventional haemostasis in thyroid surgery. METHODS Two hundred and eighty eight patients were divided in to two groups: Group 1(144 patients) conventional haemostasis, group 2 (144 patients) Oxidized cellulose + conventional haemeostasis. Preoperative and postoperative Ca levels, operation time, hospital stay, complications (bleeding, recurrent laringeal nerve injury, hypocalcemia) were evaluated. RESULTS There was no significant difference between groups in sex, preoperative and postoperative Ca levels, hospital stay, bleeding, recurrent nerve injury. The avarage age was significantly higher in group 1 compared to group 2( 52,4 years vs 49,6 years, p< 0,05). The operation time was significanly lower in group 2 compared to group 1(77,2 min.vs 87,2 min., p< 0,05). CONCLUSION Compared with conventional haemostasis methods, we think that addition Oxidized Cellulose gauze for haemostasis does not create a positive- negative difference in calcium matebolism and does not make a difference in complication rates, while shortening the operation time.