Prognostic significance of ADAM17 expression in patients with gastric cancer who underwent curative gastrectomy


Aydin D., Bilici A., Yavuzer D., KEFELİ U., Tan A., Ercelep O., ...More

CLINICAL & TRANSLATIONAL ONCOLOGY, vol.17, no.8, pp.604-611, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 8
  • Publication Date: 2015
  • Doi Number: 10.1007/s12094-015-1283-1
  • Title of Journal : CLINICAL & TRANSLATIONAL ONCOLOGY
  • Page Numbers: pp.604-611

Abstract

A disintegrin and metalloproteinase (ADAM) 17 has been indicated to be an indispensable regulator of cellular events from proliferation to migration. Although prognostic importance of ADAM17 expression has been investigated in several tumours, its clinical utility as a useful prognostic molecular marker remains unclear in gastric cancer. In the current study, we evaluated the expression of ADAM17 and its prognostic significance in gastric cancer patients after curative gastrectomy.