Prognostic significance of ADAM17 expression in patients with gastric cancer who underwent curative gastrectomy

Aydin, D.; Bilici, A.; Yavuzer, D.; KEFELİ, UMUT; Tan, A.; Ercelep, O.; Mert, A.; Yuksel, S.; Ozcelik, M.; Isik, D.; Surmeli, H.; Odabasi, H.; ALİUSTAOĞLU, MEHMET

doi:10.1007/s12094-015-1283-1

Prognostic significance of ADAM17 expression in patients with gastric cancer who underwent curative gastrectomy

Aydin D., Bilici A., Yavuzer D., KEFELİ U., Tan A., Ercelep O., ...More

CLINICAL & TRANSLATIONAL ONCOLOGY, vol.17, no.8, pp.604-611, 2015 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 17 Issue: 8
Publication Date: 2015
Doi Number: 10.1007/s12094-015-1283-1
Title of Journal : CLINICAL & TRANSLATIONAL ONCOLOGY
Page Numbers: pp.604-611

Abstract

A disintegrin and metalloproteinase (ADAM) 17 has been indicated to be an indispensable regulator of cellular events from proliferation to migration. Although prognostic importance of ADAM17 expression has been investigated in several tumours, its clinical utility as a useful prognostic molecular marker remains unclear in gastric cancer. In the current study, we evaluated the expression of ADAM17 and its prognostic significance in gastric cancer patients after curative gastrectomy.