Relationship of apelin, procalcitonin, and fetuin-A concentrations with carotid intima-media thickness in acromegaly
ANNALS OF CLINICAL BIOCHEMISTRY, vol.52, no.4, pp.456-461, 2015 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 52 Issue: 4
- Publication Date: 2015
- Doi Number: 10.1177/0004563214562431
- Journal Name: ANNALS OF CLINICAL BIOCHEMISTRY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.456-461
- Open Archive Collection: AVESIS Open Access Collection
- Kütahya Health Sciences University Affiliated: No
Abstract
Background Acromegaly is characterized by excess growth hormone and insulin-like growth factor-1 concentrations. There is conflicting evidence as to whether acromegaly is associated with an increased risk of atherosclerosis. Apelin is an adipose tissue-derived peptide that may be associated with hyperinsulinemia. Fetuin-A is a hepatocyte produced plasma glycoprotein that has an important role as a calcification inhibitor. The aim of this study was to examine apelin, fetuin-A, and procalcitonin concentrations and to assess their relationship with carotid intima medial thickness (cIMT) in subjects with acromegaly.