Clinical value of neutrophil to lymphocyte ratio in the region of lower extremity deep venous thrombosis


Akgül E.

The European Research Journal, cilt.1, no.1, ss.43-48, 2017 (Diğer Kurumların Hakemli Dergileri)

  • Cilt numarası: 1 Konu: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.18621/eurj.20175000199818
  • Dergi Adı: The European Research Journal
  • Sayfa Sayıları: ss.43-48

Özet


Objectives.


Many studies have demonstrated a significant association between cardiovascular disease and


neutrophil to lymphocyte ratio (NLR). To our knowledge, no study has been reported in patients with deep


venous thrombosis (DVT) which affecting proximal or distal leg. In this study we analyzed proximal and distal


DVT according to the NLR.


Methods.


This retrospective study was obtained from patients’ records of a tertiary


university hospital between May 2011 to January 2014. A total of 57 patients with the diagnosis of acute primary


DVT and 30 patients as control group included in the study. All of them were confirmed with lower extremity


venous duplex examinations. Of these, 37 examinations with the diagnosis of proximal DVT were compared


to 20 examinations with distal DVT. The groups compared regarding to complete blood counter values.


Results.


Mean eosinophil level was higher in the distal DVT group (0.28±0.24 vs. 0.12±0.01,


p


=0.001), whereas median


NLR were higher in the proximal DVT group than the distal DVT group (3.5 [0.5-4.3] vs. 2.3 [1.2-9.7],


respectively;


p


=0.002). In addition, median NLR, leukocyte and neutrophil counts were statistically lower in


the control group than the others (


p


=0.014,


p


=0.027 and


p


=0.004, respectively).


Conclusion.


NLR, an


inexpensive and easily measurable laboratory variable, was independently and significantly associated with


the presence and severity of DVT, especially acute proximal DVT.