SERUM LEVELS OF OXIDATIVE STRESS MARKERS IN SUBCLINICAL AND OVERT HYPOTHYROIDISM VERSUS CONTROL GROUP IN POPULATION OF KUTAHYA CITY, TURKEY


Yontem M., Arslan S., Erdogdu B. S. , KOÇAK F. E.

GOMAL JOURNAL OF MEDICAL SCIENCES, vol.19, no.4, pp.132-140, 2021 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 4
  • Publication Date: 2021
  • Doi Number: 10.46903/gjms/19.04.935
  • Title of Journal : GOMAL JOURNAL OF MEDICAL SCIENCES
  • Page Numbers: pp.132-140
  • Keywords: Hypothyroidism, Thyroid Stimulating Hormone, Oxidants, Antioxidants, Oxidative Stress, Paraoxonase-1, Total Oxidant Status, Total Antioxidant Status, Oxidative Stress Index, Arylesterase, PARAOXONASE ARYLESTERASE, ANTIOXIDANT STATUS, LDL

Abstract

Background: Overproduction of oxygen-related free radicals and inadequate antioxidant defense are critical in hypothyroidism, as they might lead to future life-threatening diseases. The objectives of this study were to compare serum levels of oxidative stress markers; total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), paraoxonase-1 (PON-1), and arylesterase (ARYL) in patients with subclinical hypothyroidism (SH) and overt hypothyroidism (OH) versus healthy controls in population of Kutahya city, Turkey.