The association of serum calcium levels with in-hospital and long-term mortality in patients with acute coronary syndrome Akut koroner sendrom hastalarında serum kalsiyum düzeyinin hastane içi ve uzun dönem mortalite ile ilişkisi
Pamukkale Medical Journal, cilt.15, sa.2, ss.267-275, 2022 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 15 Sayı: 2
- Basım Tarihi: 2022
- Doi Numarası: 10.31362/patd.1004257
- Dergi Adı: Pamukkale Medical Journal
- Derginin Tarandığı İndeksler: Scopus, Central & Eastern European Academic Source (CEEAS), TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.267-275
- Anahtar Kelimeler: Acute coronary syndrome, atherosclerosis, calcium
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Kütahya Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Objective: The relationship between serum calcium levels with cardiovascular risk factors and coronary artery disease (CAD) is well known. However, the effect of calcium on survival in patients with CAD has not been adequately evaluated. In this study, we aimed to investigate the role of calcium on mortality in the hospital and one-year follow-up after acute coronary syndrome (ACS). Materials and methods: 90 patients who underwent coronary angiography for ACS were included in this prospective observational study. Patients were classified according to their corrected serum calcium levels calculated based on albumin. In-hospital mortality and cardiac complications were defined as the primary outcome, and all-cause mortality within one year was defined as the secondary outcome in the study. The relationship between serum calcium level and mortality was evaluated by logistic regression analysis. Results: In the initial analysis, serum calcium levels were not associated with in-hospital mortality and followup period. However, in logistic regression analysis, no significant relationship was found between admission calcium levels and in-hospital mortality in ACS patients, while low calcium levels were an important risk factor for all-cause mortality within one month (p=0.038, OR=7.387, 95% CI=1.121-48.664). Serum cardiac troponin and uric acid levels showed a significant association with in-hospital mortality (p=0.018, OR=1.206, 95% CI=1.033-1.408, p=0.014, OR=1.377, 95% CI=1.067-1.776, respectively). Conclusion: Low serum calcium levels are not associated with in-hospital mortality after ACS. However, it may increase all-cause mortality rate in the first month.