The effects of anti-adhesion materials in preventing postoperative adhesion in abdominal cavity (anti-adhesion materials for postoperative adhesions)


Sahin M., Cakir M., Avsar F. M., TEKİN A., Kucukkartallar T., Akoz M.

Inflammation, vol.30, no.6, pp.244-249, 2007 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 6
  • Publication Date: 2007
  • Doi Number: 10.1007/s10753-007-9043-1
  • Journal Name: Inflammation
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.244-249
  • Keywords: Abdominal cavity, Anti-adhesion materials, Postoperative adhesion
  • Kütahya Health Sciences University Affiliated: No

Abstract

Purpose. The purpose of this study was to compare the effects of anti-adhesion materials in postoperative adhesions. Materials and Methods. Rats were assigned to five groups: Group 1: Control. Group 2: chitin layers were used. Group 3: Na-hyaluronate / carboxymethylcellulose layers were used. Group 4: Na-hyaluronate gel was poured into the abdomen. Group 5: methylprednisolone was injected. The adhesion frequency and grade were scored according to Granat. Blood was taken for Hb, AST, BUN and albumin levels determination. Findings. The adhesion frequencies (right and left) and grades were as follow in Groups; I: 82%, 91%, 2.63±1.22; II: 8.3%, 25%, 0.58±0.66; III: 17%, 33%, 1.08±1.08; IV: 50%, 58%, 1.41±1.44; V: 50%, 42%, 1.41±1.50. The adhesion phase in all study groups was found significantly low compared to control group, p<0.05. No difference was observed among serologic and hematological parameters in all groups. Conclusion. All the materials used significantly lowered the adhesion frequency and grade. © 2007 Springer Science+Business Media, LLC.