Research Information System
2. Uluslarası Genç Orad Sempozyumu, Adana, Turkey, 5 - 09 March 2024, pp.34
PURPOSE: Gardner syndrome (GS) is a phenotypic variant of familial adenomatous polyposis, characterized by numerous adenomatous polyps lining the intestinal mucosal surface with a high potential for malignancy. It is an autosomal dominant disease. Typically, patients with GS may present with osteomas of the mandible and skull, as well as epidermal cysts and fibromatosis. The purpose of this case report is to present the clinical and radiologic findings of a patient diagnosed with GS.
MATERIALS and METHODS: A 41-year-old woman applied to our clinic to replace her fixed prostheses. It was learned that the patient was diagnosed with GS due to polyps seen in the colon and that he was taking medication for this reason. Intraoral examination revealed a hard, smoothly circumscribed, bony prominences (palatinal torus, lingual torus) on palpation on the hard palate and anterior lingual mandible. The patient was imaged with orthopantomography (OPG) and cone beam computed tomography (CBCT). RESULTS: In the OPG images of the patient, a minimally sized, smoothly circumscribed radiopacity was observed in the left maxillary sinus. Additionally, minimal irregularly circumscribed radiopacities were noted at the apices of the posterior teeth in both jaws. CBCT images revealed a minimal radiopacity (possibly a bone spur or osteoma) on the lateral wall of the left maxillary sinus. Irregularly circumscribed radiopacities (potentially osteomas or hyperostosis) were also observed at the palatal aspect of tooth 15, buccal aspect of the left mandibular teeth, and buccal aspects of teeth 44 and 45, as well as at the apices of the posterior teeth in both jaws, not associated with the teeth themselves. Despite the findings, the patient declined the biopsy procedure as she did not have any complaints regarding the lesions. A follow-up appointment was scheduled for the patient after 6 months.
CONCLUSION: The primary jaw lesions associated with Gardner syndrome typically include multiple osteomas and odontomas. In cases where cutaneous cysts and osteomas result in dysfunction, surgical resection may be considered. Family screening becomes essential due to the autosomal dominant inheritance of the disease.
KEYWORDS: Gardner Syndrome, Osteoma, Cone Beam Computed Tomography