The Effect of Vitamin D Level on Blood Glucose Regulation, Lipid Profile and İnflammation Markers in Diabetic Patients: A retrospective cross-sectional study


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Erarslan S., Paşalı Kilit T., Ertürk A.

ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, vol.16, no.5, pp.345-349, 2025 (ESCI)

Abstract

Aim: In our study, we aimed to evaluate the frequency of anxiety in patients with type 2 diabetes and the effect of blood glucose regulation and vitamin B12

levels on anxiety.

Material and Methods: The study comprised 174 patients with Type 2 DM aged 18-65 years and 62 healthy controls. The study used a questionnaire form

consisting of the Sociodemographic Characteristics Form, Clinical Data Form, and Beck Anxiety Scale as a data collection tool. Mann Whitney U test, t-test for

independent variables, chi-square test, and Spearman correlation test were used to analyze the data. p<0.05 was accepted as a statistical significance value.

Results: Two hundred thirty-six people participated in our study, 174 in the case group and 62 in the control group. The mean age of the patient group was

53.7±9.0 years, and 51.1% were male. The study showed that HbA1c levels were regulated in 50.6% of diabetic patients, and vitB12 levels were adequate in

59.2%. There was no statistically significant difference between the anxiety levels and scores of Type 2 diabetic patients according to the regulation of HbA1c

levels and vitB12 levels (p>0.05). The anxiety level and scores of diabetes patients were significantly higher than the control group (p<0.005).

Discussion: Anxiety is more common in patients with diabetes. Diabetes patients should be evaluated in terms of anxiety disorders that may accompany them.

In addition, studies aimed at understanding the causes of anxiety in diabetic patients can determine the areas of intervention in this regard.

Keywords: Anxiety, Vitamin B12, Type 2 Diabetes Mellitus