10th International İzmir Congress on Medicine, Nursing, Midwifery, and Health Sciences, İzmir, Turkey, 16 - 18 December 2025, pp.407-417, (Full Text)
Tracheal, bronchial, and lung (TBL) cancer remains one of the leading causes of cancer related mortality worldwide. The aim of this study was to examine gender-specific temporal trends and the disease burden of TBL cancer attributable to air pollution across country income groups from 1990 to 2023, and to compare these patterns with Türkiye to support targeted prevention efforts and public health policymaking. Using GBD study data 1990-2023, this study examined trends in mortality and DALYs associated with TBL cancer attributable to air pollution in Türkiye and worldwide. Joinpoint regression analysis was used to detect significant temporal changes, and the APC was calculated to quantify overall trends. Results are reported with 95% uncertainty intervals, and fold changes were calculated. Results indicate between 1990 and 2023, the global burden of TBL cancer attributable to air pollution generally declined, with male mortality rates decreasing by 16% and female rates remaining stable. The death rate for males in Türkiye rose by 30% (from 9.13 to 11.88 per 100,000), while the female death rate increased by 87% (from 1.32 to 2.47 per 100,000 population) over the period. High-income countries achieved significant reductions in mortality, with rates dropping by 60% for males and 30% for females. Conversely, Türkiye’s trends align more closely with the negative trends observed in Upper-middle income countries, where male death rates rose by 13% and female rates by 12%. Despite a global decline in TBL cancer burden attributable to air pollution, Türkiye experienced a notable rise. Gender-specific joinpoint patterns reveal sustained increases in male mortality since the early 2000s and two periods of accelerated growth among females. Compared with high-income countries, which achieved substantial reductions, These results underscore the need for intensified, gender-responsive air-quality policies and cancer-prevention strategies to curb the rising burden in Türkiye.