Acute viral Hepatitis B infection after hematopoietic stem cell transplantation in a vaccine-immune patient


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Korkmaz P. , Naz H., Mehtap Ö., Çekdemir D., Mıstanoğlu Özatağ D.

ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, vol.1, no.1, pp.1-3, 2021 (Other Refereed National Journals)

  • Publication Type: Article / Case Report
  • Volume: 1 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.4328//acam.20730.
  • Title of Journal : ANNALS OF CLINICAL AND ANALYTICAL MEDICINE
  • Page Numbers: pp.1-3

Abstract

Hematopoietic stem cell transplantation is an increasingly common treatment method for benign and malignant hematological diseases. However, infections before and after transplantation are the most important causes of morbidity and mortality, working against the developments in diagnosis and treatment. The regeneration of the immune system after stem cell transplantation spans a period of 12-18 months and the risk of bacterial, fungal, and viral infection development is highest in the first 1-2 years after transplantation. While hepatitis B virus (HBV) reactivation is well defined in patients receiving immunosuppressive therapy in the literature, cases of acute viral hepatitis B (AVHB) development during immunosuppressive therapy are limited. Therefore, we present a case of AVHB developing after immunosuppressive therapy in a patient who was immunized against the HBV vaccine.