One pot synthesis of some new substituted hexahydro 2H-1,3-benzoxazine derivatives
Bollettino Chimico Farmaceutico, cilt.135, sa.8, ss.482-485, 1996 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 135 Sayı: 8
- Basım Tarihi: 1996
- Dergi Adı: Bollettino Chimico Farmaceutico
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.482-485
- Anahtar Kelimeler: benzoxazine derivatives, calcium antagonistic activity, spectra, synthesis
- Kütahya Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
In this paper, we synthesized nineteen new compounds having 2,4-diaryl-5-oxohexahydro-2H-1,3-benzoxazine structure by the reaction of 1,3-cyclohexanedione, aromatic aldehyde and ammonium acetate. In addition, we evaluated calcium antagonistic activity of these compounds versus nicardipine.