The protective effects of dexmedetomidine on hepatic ischemia reperfusion injury

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KÜÇÜK A., Yaylak F., Cavunt-Bayraktar A., TOSUN M., ARSLAN M., ÇOMU F. M. , ...More

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.115, no.11, pp.680-684, 2014 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 115 Issue: 11
  • Publication Date: 2014
  • Doi Number: 10.4149/bll_2014_132
  • Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.680-684
  • Keywords: dexmedetomidine, ischemia reperfusion, HSP60, p53, rat, ISCHEMIA/REPERFUSION INJURY, LIPID-PEROXIDATION, HEAT-SHOCK, ANTIOXIDANT ENZYMES, ALPHA-TOCOPHEROL, EXCISION-REPAIR, STRESS-RESPONSE, NITRIC-OXIDE, RAT-LIVER, IN-VIVO

Abstract

Objective: The aim of this study was to evaluate the effect of dexmedetomidine (100 mu g/kg-ip) on liver ischemia and reperfusion (I/R) in rats.