Serum prolidase, malondialdehyde and catalase levels for the evaluation of oxidative stress in patients with peripheral vertigo
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, cilt.278, sa.10, ss.3773-3776, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 278 Sayı: 10
- Basım Tarihi: 2021
- Doi Numarası: 10.1007/s00405-020-06466-x
- Dergi Adı: EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
- Sayfa Sayıları: ss.3773-3776
- Anahtar Kelimeler: Catalase, Malondialdehyde, Oxidative stress, Peripheral vertigo, Prolidase
- Kütahya Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Purpose We aimed to evaluate oxidative stress in patients with peripheral vertigo by measuring serum prolidase, malondialdehyde (MDA) and catalase levels. Methods A total of 30 patients (age: 60 <) with peripheral vertigo and 30 healthy subjects were recruited. Blood samples were collected from both groups and serum prolidase levels were measured using enzyme-linked immunosorbent assay (ELISA). MDA and catalase levels were measured by the spectrophotometric method. Results The most common cause of vertigo was BPPV (53.3%), followed by Meniere's disease (16.6%), vestibular neuritis (13.3%), lateral semicircular canal fistula (3.3%), and idiopathic vertigo (13.3%). Mean serum prolidase activity and MDA levels were significantly higher in the vertigo patients than in the control subjects (P < 0.05); however, there was no statistically significant difference in mean serum catalase levels between the groups (P > 0.05). Conclusion We concluded that serum prolidase and MDA levels may be used as markers of oxidative stress in patients with peripheral vertigo.