Acute smoking-induced alterations: In Doppler echocardiographic measurements in chronic smokers


Karakaya O., Barutcu I., Esen A. M., Kaya D., Turkmen M., Melek M., ...More

Texas Heart Institute Journal, vol.33, no.2, pp.134-138, 2006 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 2
  • Publication Date: 2006
  • Journal Name: Texas Heart Institute Journal
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.134-138
  • Keywords: Blood flow velocity, Diastole/drug effects, Echocardiography, Doppler, Heart rate/drug effects, Heart ventricles/drug effects, Hemodynamic processes, Myocardial contraction/drug effects, Smoking/adverse effects, Sympathetic nervous system/drug effects
  • Kütahya Health Sciences University Affiliated: No

Abstract

Acute effects of smoking on left ventricular function have been studied previously. However, effects on right ventricular function have not yet been investigated. In this study, we attempted to investigate, through a combination of conventional and tissue Doppler imaging (TDI), the acute effects of smoking on both left and right ventricular function in chronic smokers. Thirty chronic smokers (with smoking habits of ≥1 pack/day for 7.4 ± 1.3 years) underwent a complete transthoracic echocardiographic examination (2-dimensional, pulsed-wave Doppler transmitral and transtricuspid recordings, and TDI recordings of mitral and tricuspid annular velocities) by 3.5-MHz sector transducer. Pulsed-wave Doppler indices of left and right ventricular diastolic function - such as mitral and tricuspid inflows, peak early (E) and late (A) velocities, and E/A ratios - were obtained by conventional Doppler and TDI. Echocardiographic indices of the left and right ventricles - including isovolumetric relaxation time, isovolumetric contraction time, ejection time, and myocardial performance index of right ventricle - were also measured before and 30 minutes after each subject smoked a cigarette. Both mitral and tricuspid inflow measurements changed significantly after smoking a cigarette. Among the TDI measurements, mitral lateral annulus and tricuspid lateral annulus (diastolic, but not systolic) velocities changed after smoking a cigarette. Also, the right ventricular myocardial performance index increased immediately after smoking a cigarette. We found that acute cigarette smoking impaired both left and right ventricular diastolic function in chronic smokers. © 2006 by the Texas Heart® Institute.