Effect of the number of portal area on modified histological activity index of viral hepatitis and histological findings

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GÜRBÜZEL M., SAYGI G., ÖZYİGİT F., OGUZÖNCÜL A., GÜLŞEN H., BAŞARAN S.

NIGERIAN JOURNAL OF CLINICAL PRACTICE, vol.17, no.1, pp.56-61, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.4103/1119-3077.122840
  • Journal Name: NIGERIAN JOURNAL OF CLINICAL PRACTICE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.56-61
  • Kütahya Health Sciences University Affiliated: Yes

Abstract

Aim: Viral hepatitis is one of the most important causes of chronic hepatitis. Liver biopsy is used to verify clinical diagnosis and to evaluate necroinflammation and fibrosis. Biopsy is the guide for therapy and can be performed also after treatment to assess the effect of therapy on liver. This paper aimed to explore histopathological characteristics of biopsy samples, which had been referred to our department with the clinical diagnosis of chronic viral hepatitis, in reference to Ishak Modified Hepatic Activity Index (IMHAI), as well as to compare inflammatory scores and stages in the groups created according to the number of portal area (PA).