Clomiphene Citrate Treatment Cycle Outcomes of Polycystic Ovary Syndrome Patients Based on Basal High Sensitive C-Reactive Protein Levels: A Cross-Sectional Study


Kahyaoglu S., Yumusak O. H. , Ozyer S., Pekcan M. K. , Erel M., Cicek M. N. , ...More

INTERNATIONAL JOURNAL OF FERTILITY & STERILITY, vol.10, no.4, pp.320-326, 2017 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 4
  • Publication Date: 2017
  • Title of Journal : INTERNATIONAL JOURNAL OF FERTILITY & STERILITY
  • Page Numbers: pp.320-326

Abstract

Background: Polycystic ovary syndrome (PCOS) is highly associated with an ovulatory infertility, features of the metabolic syndrome, including obesity, insulin resistance and dyslipidemia. Serum concentrations of high sensitive C-reactive protein (hs-CRP) were significantly higher in obese than in non-obese PCOS patients at baseline, suggesting a relationship between elevated hs-CRP levels and obesity. The aim of this study was to evaluate whether cycle day 3 hs-CRP levels before clomiphene citrate (CC) treatment would predict cycle outcomes in women with PCOS.