IDH1 mutations is prognostic marker for primary glioblastoma multiforme but MGMT hypermethylation is not prognostic for primary glioblastoma multiforme


KALKAN R., ATLI E. İ. , ÖZDEMİR M., ÇİFTÇİ E., AYDIN H. E. , ARTAN S., ...Daha Fazla

GENE, cilt.554, ss.81-86, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 554 Konu: 1
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.gene.2014.10.027
  • Dergi Adı: GENE
  • Sayfa Sayıları: ss.81-86

Özet

Purpose: To establish the frequency of IDH1 mutations and MGMT methylation in primary glioblastomas. Experimental design: We screened primary glioblastoma multiforme (GBM) in a population-based study for IDH1 mutations and MGMT methylation and correlated them with clinical data.