IDH1 mutations is prognostic marker for primary glioblastoma multiforme but MGMT hypermethylation is not prognostic for primary glioblastoma multiforme


KALKAN R., ATLI E. İ. , ÖZDEMİR M., ÇİFTÇİ E., AYDIN H. E. , ARTAN S., ...More

GENE, vol.554, no.1, pp.81-86, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 554 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.1016/j.gene.2014.10.027
  • Title of Journal : GENE
  • Page Numbers: pp.81-86

Abstract

Purpose: To establish the frequency of IDH1 mutations and MGMT methylation in primary glioblastomas. Experimental design: We screened primary glioblastoma multiforme (GBM) in a population-based study for IDH1 mutations and MGMT methylation and correlated them with clinical data.