Effects of alprostadil and iloprost on renal, lung, and skeletal muscle injury following hindlimb ischemia-reperfusion injury in rats

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ERER D., ÖZER A., DEMİRTAŞ H., Gonul I. I., KARA H., ARPACI A. H., ...More

DRUG DESIGN DEVELOPMENT AND THERAPY, vol.10, pp.2651-2658, 2016 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 10
• Publication Date: 2016
• Doi Number: 10.2147/dddt.s110529
• Journal Name: DRUG DESIGN DEVELOPMENT AND THERAPY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.2651-2658
• Keywords: alprostadil, iloprost, ischemia reperfusion injury, rat, renal, lung, skeletal muscle, PHENOMENON SECONDARY, RAYNAUDS-PHENOMENON, SYSTEMIC-SCLEROSIS, ADHESION, ISCHEMIA/REPERFUSION, TRANSPLANTATION, METABOLISM, INFUSION, KIDNEY, ACID
• Kütahya Health Sciences University Affiliated: No

Abstract

Objectives: To evaluate the effects of alprostadil (prostaglandin [PGE1] analog) and iloprost (prostacyclin [PGI2] analog) on renal, lung, and skeletal muscle tissues after ischemia reperfusion (I/R) injury in an experimental rat model.