Fascin expression in cholesteatoma: correlation with destruction of the ossicular chain and extent of disease
CLINICAL OTOLARYNGOLOGY, cilt.40, sa.4, ss.335-340, 2015 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 40 Sayı: 4
- Basım Tarihi: 2015
- Doi Numarası: 10.1111/coa.12373
- Dergi Adı: CLINICAL OTOLARYNGOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.335-340
- Kütahya Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
ObjectiveFascin is an actin-bundling protein found in cell membrane protrusions and increases cell motility. The expression of fascin in epithelial neoplasms has been described only recently. No data are available concerning the role of this protein in invasive cholesteatoma. Thus, we investigated the expression of fascin in cholesteatoma tissue and the relationship between fascin expression and intraoperative evaluation of the destruction of the ossicular chain and extent of disease.