Serum Maresin 1 levels in idiopathic acute anterior uveitis patients Niveaux sériques de marésine 1 chez les patients atteints d'uvéite antérieure aiguë idiopathique


Gül F., Kobat S., Kasar K., Aydin S., AKKOÇ R. F.

Journal Francais d'Ophtalmologie, cilt.45, sa.10, ss.1160-1170, 2022 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 10
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1016/j.jfo.2022.05.020
  • Dergi Adı: Journal Francais d'Ophtalmologie
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.1160-1170
  • Anahtar Kelimeler: CRP, ESR, Idiopathic, Maresin, Uveitis
  • Kütahya Sağlık Bilimleri Üniversitesi Adresli: Hayır

Özet

Purpose: The purpose of the present study is to assess the levels of Maresin 1 (MaR1) in patients with idiopathic acute anterior uveitis (IAAU) and to compare the MaR1 results with healthy controls. Methods: This study includes 24 patients with idiopathic AAU and 24 healty controls (C). The serum MaR1 levels were analyzed using enzyme-linked immunosorbent assays (ELISA). The erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels were measured at the time of diagnosis. Results: MaR1 levels were statistically significant when the IAAU group was compared with group C (P < 0.001). When idiopathic AAU patients were compared with group C, no statistically significant difference was found between ESR and CRP levels (P = 0.086, P = 0.549 respectively). Conclusion: Serum MaR1 levels are an important biomarker of disease in patients with idiopathic AAU.