Cytotoxic, anti-proliferative and apoptotic effects of noscapine on human estrogen receptor positive (MCF-7) and negative (MDA-MB-231) breast cancer cell lines


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Kocak C., Kocak F. E. , Ozturk B., Tekin G., Vatansev H.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.121, ss.43-50, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 121
  • Basım Tarihi: 2020
  • Doi Numarası: 10.4149/bll_2020_007
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Sayfa Sayısı: ss.43-50

Özet

AIM: Noscapine, a naturally occurring alkaloid obtained from opium poppy, is a microtubule-targeting agent. This study is aimed to investigate the effects of noscapine on human breast cancer cell lines by comparing them with those of tamoxifen and docetaxel.