Effects of Interactions among Gene Polymorphisms of the Renin-Angiotensin-Aldosterone System on Hypertension in Turkish People from Southeast Anatolia
REVISTA ROMANA DE MEDICINA DE LABORATOR, cilt.27, sa.2, ss.159-168, 2019 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 27 Sayı: 2
- Basım Tarihi: 2019
- Doi Numarası: 10.2478/rrlm-2019-0011
- Dergi Adı: REVISTA ROMANA DE MEDICINA DE LABORATOR
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
- Sayfa Sayıları: ss.159-168
- Anahtar Kelimeler: hypertension, renin-angiotensin-aldosterone system (RAAS), genetic variations, ACE I/D, haplotype, CONVERTING-ENZYME GENE, I/D POLYMORPHISM, INSERTION/DELETION POLYMORPHISM, BLOOD-PRESSURE, ASSOCIATION, ACE, FREQUENCY, CHINESE, STROKE, HAN
- Kütahya Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Introduction: Hypertension (HT) is characterized by high blood pressure. The reninangiotensin-aldosterone system (RAAS) plays a crucial role in blood pressure (BP) regulation by maintaining vascular tone and the water-sodium balance. We aimed to investigate whether there is any relation between AGT (M235T), ACE (I/D), and AGTR1 (A1166C) genetic polymorphisms and hypertension among Turkish people from Southeast Anatolia.