Methotrexate toxicity presenting as cutaneous ulcerations on psoriatic plaques
CUTANEOUS AND OCULAR TOXICOLOGY, cilt.32, sa.4, ss.333-335, 2013 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 32 Sayı: 4
- Basım Tarihi: 2013
- Doi Numarası: 10.3109/15569527.2013.779278
- Dergi Adı: CUTANEOUS AND OCULAR TOXICOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.333-335
- Anahtar Kelimeler: Cutaneous ulceration, methotrexate, toxicity, LOW-DOSE METHOTREXATE, PATIENT, SIGN, EROSION
- Kütahya Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Methotrexate (MTX) is an effective but potentially toxic treatment for psoriasis. We describe a patient who administered 20 mg daily of MTX for 5 d and presented with ulcerated and necrotic lesions on the psoriatic plaques, mouth erosions and hair loss. However, his psoriatic plaques and ulcerations totally healed rapidly within two weeks and no recurrence has been observed for the 6 months of follow up.