Bioprostethic mitral valve thrombosis due to oral contraceptive drug use and management with ultra-slow thrombolytic therapy

Yesin M., Kalçik M., Gündüz S., ASTARCIOĞLU M. A., Gürsoy M. O., Karakoyun S., ...More

Blood Coagulation and Fibrinolysis, vol.27, no.2, pp.220-222, 2016 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.1097/mbc.0000000000000420
  • Journal Name: Blood Coagulation and Fibrinolysis
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.220-222
  • Keywords: bioprosthetic valve, oral contraceptive drugs, thrombolytic therapy, thrombosis, tissue-type plasminogen activator
  • Kütahya Health Sciences University Affiliated: Yes

Abstract

Prosthetic valve thrombosis is a severe complication, which usually occurs in inadequately anticoagulated patients. Mechanical valve thrombosis is more common than bioprosthetic valve thrombosis (BVT). Oral contraceptive drugs are associated with increased risk of thromboembolism in women. The possible association between oral contraceptive drug use and BVT has never been reported before. We present a case of obstructive BVT occurring after the use of an oral contraceptive drug and successful management with ultra-slow thrombolytic therapy.