An evaluation of the neutrophil/lymphocyte ratio in patients with hashimoto's thyroiditis
Acta Medica Mediterranea, cilt.30, sa.2, ss.457-460, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 30 Sayı: 2
- Basım Tarihi: 2014
- Dergi Adı: Acta Medica Mediterranea
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.457-460
- Anahtar Kelimeler: Chronic inflammation, Hashimoto's thyroiditis, Neutrophil/lymphocyte ratio
- Kütahya Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Aim: Hashimoto's thyroiditis (HT) is a chronic autoimmune thyroid disease in which genetic and environmental factors play a role in the etiology. In addition, it remains the leading cause of hypothyroidism throughout the world. The neutrophil/lymphocyte ratio (NLR) is a cheap, simple measurement that can be used to indicate systemic inflammation associated with this disease. Materials and methods: 81 patients diagnosed with Hashimoto's thyroiditis and 54 healthy individuals were enrolled in the study. We recorded the results of the free triiodothyronine (FT3), free thyroxin (FT4), thyroid-stimulating hormone (TSH), anti-thyroid peroxidase (anti-TPO), anti-thyroglobulin (anti-TG), complete blood count (CBC), and C-reactive protein (CRP) measurements in both groups and also calculated the NLR. Results: The NLR was statistically significantly higher in the HT patients than the controls (2.37±1.46 versus 1.80±0.67, respectively; p<0.003). Furthermore, a negative but statistically insignificant correlation was determined between the NLR and anti-TG and anti-TPO. Conclusion: NLR can be a valuable, practical parameter for monitoring HT as well as other autoimmune and chronic inflammatory diseases.