Causapedia, no.8, pp.41-44, 2019 (Peer-Reviewed Journal)
Parathyroid carcinoma is a very rare endocrine malignancy with less than 1/1.000.000 incidence rate. Clinical findings are due to the effects of increased parathormone and blood calcium levels on target organs. The treatment of parathyroid carcinoma is en bloc resection. Severe hypercalcemia (15.0 mg/dl) and elevated parathormone levels (1520 pg/ml) weredetected in our patient who presented with kidney stone complaints. The patient was preliminarily diagnosed withparathyroid adenoma by neck ultrasonography and parathyroid scintigraphy. Ipsilateral thyroidectomy + parathyroidectomy + selective neck dissection were performed in the patient who was diagnosed as parathyroidcarcinoma by intraoperative frozensection analysis.Thepatient is under follow-up without any disease at the 6-month routine calcium and parathormone level controls.
As a result, parathyroidcarcinoma is averyrareendocrinemalignancyand an endocrine disorder that should be kept in mind in cases with blood calcium levels above 15 mg / dl and severe hyperparathyroidism, which should be routinely controlled for postoperative recurrence.