Is prostate biopsy safe in the elderly?

Alkış O. , Başer A., İvelik H. İ. , Aras B. , Sevim M. , Kartal İ. G.

Pamukkale Tıp Dergisi, vol.14, no.2, pp.3-13, 2021 (National Refreed University Journal)

  • Publication Type: Article / Article
  • Volume: 14 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.31362/patd.827622
  • Title of Journal : Pamukkale Tıp Dergisi
  • Page Numbers: pp.3-13


Aim: The study was aimed to investigate the safety of the transrectal ultrasound-guided prostate needle biopsy in the elderly. Material-method: Five hundered fifteen patients, who underwent prostate biopsy between 2017-2020, were included in the study. All patients' demographic data, comorbidities, laboratory findings, prostate volumes, prostate biopsy pathology results, and post-biopsy complications were retrospectively analyzed. The patients were divided into 2 groups: group-1 consisting of patients under the age of 65 and group-2 with above the age of 65. Results: There were 244 in group-1 and 271 patients in group-2. The mean age of group-1 was 59.50±3.98, group-2 was 71.45±4.57 years. In group-1, post-biopsy fever was observed in 5 (2%), hematuria in 44 (18%), hemospermia in 79 (32.4%), and rectal bleeding in 7 (2.9%) patients. In group-2, post-biopsy fever was observed in 15 (5.5%), hematuria in 69 (25.5%), hemospermia in 21 (7.7%), and rectal bleeding in 11 (4.1%) patients. The severe sepsis findings were observed in 2 patients (0.2%) in group-1 and 6 (2.2%) in group-2. In the logistic-regression-analysis, it was determined that the risk of complication increased significantly as the age, PSA, and higher PSA density. Conclusion: In our study, it was revealed that the risk of complications was higher in the elderly and that the complications observed may be more seriously. Therefore, we consider that a more careful approach should be taken in elderly patients to prevent the complications related with prostate biopsy.