Background: The first wave of COVID-19 pandemic began to spread in Turkey in March 2020. As one of the first pandemic hospitals, very intense patient admissions have been made to our outpatient clinics in this period. For better understanding the disease characteristics, we investigated the clinical findings, comorbidities, and radiological pulmonary involvement of the COVID-19 patients.
Methods: The SARS-CoV-2 RT-PCR test results of 6966 patients, applied to Kartal Lutfi Kırdar City Hospital InfectiousDiseases and Clinical Microbiology COVID-19 outpatient clinics between March and June 2020, were analyzed retrospectively. Demographic, clinical, and thoracic computed tomography data of the patients with positive test results were evaluated.
Results: 2672(38.4%) patients were SARS-CoV-2 RT-PCR positive (1465 males, 1207 females). The mean age of the patients with a definite diagnosis of COVID-19 was 40.4±14.5 years (12-94 years). There was a statistically significant relationship between the age and COVID-19 (75.3% were >65 years, p<0.001). The main clinical findings were fever (n:2437, 91.2%), cough (n:2013, 75.3%), dyspnea (n:809, 30.2%), sore throat (n:257, 9.6%), weakness (n:244, 9.1%), myalgia (n:228, 8.5%), nausea/vomiting (n:135, 5.1%), diarrhea (n:80, 3%), anosmia (n:54, 2%), and loss of taste (n:54, 2%). The comorbidities found in our COVID-19 patients were hypertension(HT) (n:94, 3.5%), diabetes mellitus(DM) (n:70, 2.6%), chronic obstructive pulmonary disease(COPD) (n:68, 2.5%), coronary artery disease(CAD) (n:32, 1.2%) and malignancy (n:16, 0.6%). 4113 patients (75.2%), out of 5484 patients who had thorax CT, had COVID-19 compatible radiological involvement, with 3315(80.6%) positive and 798(19.4%) negative SARS-CoV-2 RT-PCR test results.
Conclusion: The most frequent symptoms in the patients admitted to our hospital in the first wave of pandemic were fever, cough, dyspnea, sore throat, and weakness. Despite lockdown, the elderly above 65 years were most affected. The rate of COVID-19 compliant radiological involvement was moderately high. The most common comorbidities were HT, DM, COPD, CAD and malignancy.