Effects of various acidic and alkaline solutions used to dissolve urinary calculi on the rabbit urothelium
Urologia Internationalis, vol.45, no.5, pp.293-297, 1990 (Scopus)
- Publication Type: Article / Article
- Volume: 45 Issue: 5
- Publication Date: 1990
- Doi Number: 10.1159/000281723
- Journal Name: Urologia Internationalis
- Journal Indexes: Scopus
- Page Numbers: pp.293-297
- Keywords: Acid solutions, Alkaline solutions, Rabbit, Urinary calculi, Urothelium
- Kütahya Health Sciences University Affiliated: Yes
Abstract
It is well known that infection-induced stones (apatite, struvite), uric acid and cystine calculi in the urinary tract can be managed by the use of certain chemical solutions. We investigated the effects of various acidic and alkaline solutions on the rabbit urothelium. Acidic solutions (pH: 4.2) caused more urothelial injury as compared to alkaline solutions (pH: 7.6). Ureteral injury was more severe than the bladder injury. Magnesium-containing solutions caused less injury to the urothelium. © 1990 S. Karger AG, Basel.