Silymarin attenuates the renal ischemia/reperfusion injury-induced morphological changes in the rat kidney


ŞENTÜRK H., KABAY Ş. , BAYRAMOĞLU G., ÖZDEN H., YAYLAK F. , YÜCEL M., ...More

WORLD JOURNAL OF UROLOGY, vol.26, no.4, pp.401-407, 2008 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 4
  • Publication Date: 2008
  • Doi Number: 10.1007/s00345-008-0256-1
  • Title of Journal : WORLD JOURNAL OF UROLOGY
  • Page Numbers: pp.401-407

Abstract

Objectives Renal ischemia/reperfusion (I/R) injury is associated with increased mortality and morbidity rates due to acute renal failure (ARF). Oxidative stress induced with renal I/R injury directly affects glomerular and tubular epithelium through reactive oxygen species. Several studies have been directed to the treatment of renal I/R injury. The aim of this study was to test the attenuation with silymarin (SM) treatment of renal I/R injury-induced morphological changes in the rat kidney.