Comparison of the Effects of Lamotrigine and Valproate on the Pentylenetetrazole-Induced Seizures and Behaviour of Immature Rats


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Göl M. F. , ERDOĞAN F. F. , KÜÇÜK A. , GÖLGELİ A.

EPILEPSI, cilt.24, ss.120-126, 2018 (ESCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 24 Konu: 3
  • Basım Tarihi: 2018
  • Doi Numarası: 10.14744/epilepsi.2018.55477
  • Dergi Adı: EPILEPSI
  • Sayfa Sayısı: ss.120-126

Özet

Objectives: Epileptics, especially children, are more prone to behavioural deficits. Epilepsy related factors, psychosocial problems, treatment side effects may aggravate such deficits. We investigated the effects of lamotrigine and valproate on the behaviour, and pentylenetetrazol (PTZ)-induced seizures on immature rats (21-day-old male).