Histopathological Evaluation of the Effects of CAPE in Experimental Spinal Cord Injury

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AYDIN H. E., ÖZKARA E., ÖZBEK Z., VURAL M., Burukoglu D., ARSLANTAŞ A., ...More

TURKISH NEUROSURGERY, vol.26, no.3, pp.437-444, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.5137/1019-5149.jtn.11255-14.0
  • Journal Name: TURKISH NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.437-444
  • Kütahya Health Sciences University Affiliated: No

Abstract

AIM: Spinal cord injuries negatively affect the individuals and the life quality of their families due to neurological deficits caused by trauma. The prevalence of spinal cord injury is 15-45/1 million in the world. Caffeic acid phenethyl ester (CAPE) is the most active component of propolis and has neuroprotective, anti-oxidant and anti-apoptotic effects. Our aim was to determine the effects of CAPE on the prevention of secondary injury and to compare with methylprednisolone.