Angio-oedema as an unusual tolerable side effect of voriconazole therapy.

Gencer S., Ozer S., Demirhan G., AK Ö. , Batirel A.

Journal of medical microbiology, cilt.57, sa.8, ss.1028-1031, 2008 (SCI Expanded İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Konu: 8
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1099/jmm.0.47299-0
  • Dergi Adı: Journal of medical microbiology
  • Sayfa Sayıları: ss.1028-1031


Voriconazole (VRC) has not previously been reported to cause angio-oedema. Here, we report a case of angio-oedema associated with VRC therapy. A 37-year-old woman with relapsing invasive vertebral aspergillosis received intravenous VRC and developed angio-oedema 10 days after starting therapy. This condition rapidly diminished after administration of intravenous antihistaminics and did not necessitate cessation of VRC treatment. The treatment was continued for 6 months without recurrence of the symptoms. After 18 months, the patient was in good health. To our knowledge, this is the first report of an angio-oedema associated with VRC.