Determination of apoptosis and cell cycle modulators (p16, p21, p27, p53, BCL-2, Bax, BCL-xL, and cyclin D1) in thyroid follicular carcinoma, follicular adenoma, and adenomatous nodules via a tissue microarray method
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Temiz P., Akkas G., Nese N., Ugur Duman F., Karakas C., Erhan Y.
TURKISH JOURNAL OF MEDICAL SCIENCES, vol.45, no.4, pp.865-871, 2015 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
45
Issue:
4
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Publication Date:
2015
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Doi Number:
10.3906/sag-1406-48
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Journal Name:
TURKISH JOURNAL OF MEDICAL SCIENCES
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
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Page Numbers:
pp.865-871
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Keywords:
Thyroid, follicular neoplasm, p16, p21, p27, p53, Bcl-2, Bax, Bcl-XL, Cyclin D1, immunohistochemistry, tissue microarray, PROTEIN EXPRESSION, PROGNOSTIC-FACTOR, IMMUNOHISTOCHEMICAL EXPRESSION, PAPILLARY MICROCARCINOMA, PROLIFERATIVE ACTIVITY, CLINICAL-SIGNIFICANCE, TRANSCRIPTION FACTOR, REGULATORY PROTEINS, BENIGN, TUMORS
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Kütahya Health Sciences University Affiliated:
No
Abstract
Background/aim: To identify the role of gene products associated with apoptosis and cell cycle in the pathogenesis of thyroid follicular neoplasm.