Determination of apoptosis and cell cycle modulators (p16, p21, p27, p53, BCL-2, Bax, BCL-xL, and cyclin D1) in thyroid follicular carcinoma, follicular adenoma, and adenomatous nodules via a tissue microarray method

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Temiz P., Akkas G. , Nese N., Ugur Duman F., Karakas C., Erhan Y.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.45, no.4, pp.865-871, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.3906/sag-1406-48
  • Title of Journal : TURKISH JOURNAL OF MEDICAL SCIENCES
  • Page Numbers: pp.865-871
  • Keywords: Thyroid, follicular neoplasm, p16, p21, p27, p53, Bcl-2, Bax, Bcl-XL, Cyclin D1, immunohistochemistry, tissue microarray, PROTEIN EXPRESSION, PROGNOSTIC-FACTOR, IMMUNOHISTOCHEMICAL EXPRESSION, PAPILLARY MICROCARCINOMA, PROLIFERATIVE ACTIVITY, CLINICAL-SIGNIFICANCE, TRANSCRIPTION FACTOR, REGULATORY PROTEINS, BENIGN, TUMORS

Abstract

Background/aim: To identify the role of gene products associated with apoptosis and cell cycle in the pathogenesis of thyroid follicular neoplasm.