Objective: Endoscopic Retrograde Cholangio Pancreatography (ERCP) is a method that helps to show pancreas, gall bladder and intra and extra hepatic bile ducts. Recently ERCP is used for the treatment of pancreaticobilier system pathologies rather than diagnosis. • Material and Method: With extra hepatic cholestasis, 118 patients who hospitalized to the Gastroenterology Clinic of Stileyman Demirel University Medical Faculty were included in to the study. Forty-eight (40.7%) of patients were men and 70 (59.3%) of them were women. • Results: Totally 123 FRCP procedures were performed; seventy-one choledochal stone, 20 malign stenosis, 8 benign stenosis, 9 Oddi fibrosis, 7 postoperative biliary fistulas, 1 choledochoduodenal fistula, 1 ectopic opening anomaly, 1 Fasciola hepatica were found. There was more than one pathology in some patients; totally 93 patients were having choledochal stone. Diverticulum was detected in 22 patients. Mild complications were seen in six patients. ERCP was unsuccessful in 17 patients. • Conclusion: Serious complications may be seen such as perforation, sepsis and even mortality during the ERCP procedure. More experienced endoscopist and team, careful follow-up during ERCP procedure and in service may increase the success of procedure as well as decrease the complications to the minimal.