Objective: The aim of this study is to compare the duration of surgery and anesthesia, complication rates and the amount of anesthetic drugs used and the cost in laparoscopic tubal ligation cases with and without the use of manipulator. This retrospective case control study included women who underwent elective interval laparoscopic tubal ligation. Material and Methods: The time between intubation and the onset of surgery, duration of surgery (main operation time) and intubation-extubation (total operation time ' duration of anesthesia) were recorded in the operating room. Results: Demographic datas were similar between the patients with and without manipulators (p> 0.05). In the non-manipulator group, intubation to beginning of surgery time, main operation time, total anesthesia time was found to be shorter (p <0.001, p <0.001, p <0.001, respectively). Postoperative hospital stay, the amount of parenteral anesthetic drug used, the need for postoperative parenteral analgesics, the number of laparoscopic ports used and the complication rates were similar between the two groups (p> 0.05). Sevoflurane use was found to be less in the non-manipulator group (p <0.001). Conclusions: In laparoscopic tubal ligation operation where no uterine manipulator is used, anesthesia and total surgery times are approximately 8 minutes shorter. The use of uterine manipulator increases the duration of surgery and the amount of sevoflurane used. Laparoscopic tubal ligation without uterine manipulator may be considered in cases where severe adhesions are not anticipated and no additional intervention is planned. However, avoidance of manipulator use may have the advantage of time and cost savings.