Tear function in patients with chronic renal failure undergoing hemodialysis

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Aktas S., Sagdik H. M. , Aktas H., Gulcan E., Tetikoglu M., Cosgun S. , ...More

RENAL FAILURE, vol.37, no.2, pp.245-248, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.3109/0886022x.2014.982487
  • Title of Journal : RENAL FAILURE
  • Page Numbers: pp.245-248
  • Keywords: Chronic renal failure, dry eye, ocular surface disease index, Schirmer test, tear break-up time, OCULAR SURFACE, CORNEAL CALCIFICATION, DISEASE, EYE, HYPEROSMOLARITY, INSUFFICIENCY, CONJUNCTIVAL, DISORDERS


Objectives: To evaluate dry eye symptoms and clinical tear film alterations in patients with chronic renal failure (CRF). Materials and methods: Thirty-five non-diabetic CRF patients undergoing hemodialysis, and 31 healthy individuals were enrolled. An ocular surface disease index questionnaire (OSDI) was administered, and after a complete ocular examination, Schirmer and tear break-up time (TBUT) tests were performed. Results: OSDI scores were significantly higher (p < 0.01) and TBUT tests were significantly lower (p = 0.01) in CRF patients than in the control group. Schirmer test results were also lower in the CRF patients group, but lacked statistical significance (p = 0.20). Conclusion: Patients with CRF should be advised to obtain an ophthalmic examination, especially for dry eye.