Research Information System
Anadolu Üniversitesi Bilim ve Teknoloji Dergisi :A-Uygulamalı Bilimler ve Mühendislik, no.3 (2), pp.297-306, 2002 (Peer-Reviewed Journal)
This study was carried out in the Department of Pathology, Faculty of Medicine at Trakya University and Department of Biology, Faculty of Art and Sciences at Trakya University in 1991-1995. In the study, normal and abnormal tissue samples obtained from the patients, whose were suspected for cancer were wed. Initially, pathological characters of the tissues were identified. Then these tissues were analysed by using Flow cytometry technique. Also, Flow cytometry technique was used in order to show DNA index of the cells. Also, it can be used to show the changes in the cell cycle phases, which related to produce cancerous tissue. Results shoved statistically significant differences in DNA index analyses and in cell cycle values. However, it can be said that this method alone, cannot be reliable enough in clinical diagnosis. Because some values were deviated from the mean values. Therefore in order to increase the reliability of the method, a standardization, which may be supported by some other techniques, is required. Moreover, the role of G6 cells on the ratio differences of G1+G6 cells values in terms of normal and abnormal cells should be determined.