Assessment of the effects of levosimendan and thymoquinone on lung injury after myocardial ischemia reperfusion in rats

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SEZEN Ş. C., KÜÇÜK A., ÖZER A., Kılıç Y., Mardin B., ALKAN M., ...More

DRUG DESIGN DEVELOPMENT AND THERAPY, vol.12, pp.1347-1352, 2018 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 12
• Publication Date: 2018
• Doi Number: 10.2147/dddt.s160092
• Journal Name: DRUG DESIGN DEVELOPMENT AND THERAPY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1347-1352
• Keywords: ischemia reperfusion, levosimendan, thymoquinone, lung, caspase 3, p53, ISCHEMIA/REPERFUSION INJURY, OXIDATIVE STRESS, MECHANISMS, CARDIOPROTECTION, KIDNEY, DYSFUNCTION, EXPRESSION, INFARCTION, IMPROVES, DEATH
• Kütahya Health Sciences University Affiliated: Yes

Abstract

Aim: The aim of this study was to investigate the effects of levosimendan and thymoquinone (TQ) on lung injury after myocardial ischemia/reperfusion (I/R).