Effect of alprostadil on erythrocyte deformability in ischemia reperfusion injury

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KARA H., ÖZER A., ARPACI A. H., Demirtaş H., ÇOMU F. M., OKTAR G. L., ...More

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.116, no.8, pp.509-511, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 116 Issue: 8
  • Publication Date: 2015
  • Doi Number: 10.4149/bll_2015_099
  • Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.509-511
  • Keywords: erythrocyte deformability, ischemia reperfusion, alprostadil, rat, PROSTAGLANDIN E(1), SKELETAL-MUSCLE, ILOPROST, LUNG
  • Kütahya Health Sciences University Affiliated: No

Abstract

BACKGROUND: Ischemia reperfusion injury (I/R) in lower extremity is a frequent and important clinical phenomenon. Protective effect of alprostadil on local and distant organ injury due to I/R has been well-documented but its effect on erythrocyte deformability needs further investigation. Our aim was to investigate the effect of alprostadil on erythrocyte deformability in infrarenal aorta of rats undergoing I/R.