Acute fluconazole toxicity: a case presenting with protean manifestations including systemic and neurologic symptoms

Eskut N., Gedizlioglu M., Unal O., Ozlu C. , Ergene U.

POSTGRADUATE MEDICINE, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume:
  • Publication Date: 2020
  • Doi Number: 10.1080/00325481.2020.1840830
  • Title of Journal : POSTGRADUATE MEDICINE


Neurologic adverse effects of triazole antifungal compounds used for the treatment of systemic and deep mycoses are relatively rare. The most common presentation is the involvement of peripheral nervous system, usually presenting with subjective symptoms such as paresthesia, dysesthesia, or numbness. Among these compounds, fluconazole has relatively more frequent neurological adverse reactions.