Acute fluconazole toxicity: a case presenting with protean manifestations including systemic and neurologic symptoms


Eskut N., Gedizlioglu M., Unal O., Ozlu C., Ergene U.

POSTGRADUATE MEDICINE, cilt.133, sa.2, ss.250-252, 2021 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 133 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1080/00325481.2020.1840830
  • Dergi Adı: POSTGRADUATE MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, CINAHL, EBSCO Education Source, Educational research abstracts (ERA), EMBASE, International Pharmaceutical Abstracts, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.250-252
  • Anahtar Kelimeler: acute renal insufficiency, adverse reactions, Fluconazole, polyneuropathy, thrombotic thrombocytopenic purpura
  • Kütahya Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Neurologic adverse effects of triazole antifungal compounds used for the treatment of systemic and deep mycoses are relatively rare. The most common presentation is the involvement of peripheral nervous system, usually presenting with subjective symptoms such as paresthesia, dysesthesia, or numbness. Among these compounds, fluconazole has relatively more frequent neurological adverse reactions.