Acute fluconazole toxicity: a case presenting with protean manifestations including systemic and neurologic symptoms


Eskut N., Gedizlioglu M., Unal O., Ozlu C. , Ergene U.

POSTGRADUATE MEDICINE, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası:
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1080/00325481.2020.1840830
  • Dergi Adı: POSTGRADUATE MEDICINE

Özet

Neurologic adverse effects of triazole antifungal compounds used for the treatment of systemic and deep mycoses are relatively rare. The most common presentation is the involvement of peripheral nervous system, usually presenting with subjective symptoms such as paresthesia, dysesthesia, or numbness. Among these compounds, fluconazole has relatively more frequent neurological adverse reactions.