pamukkale tıp dergisi, cilt.4, sa.3, ss.9, 2021 (Hakemli Üniversite Dergisi)
Objective: Neutrophile-Lymphocyte (NLR) and Platelet-Lymphocyte ratio (PLR)
comparison is an easy to use and cost-effective method in diagnosis of some cancers
and diseases. In this study, we aimed to investigate if NLR/PLR ratio evaluation could
be utilized in diagnosis of testicular malignencies especially in early-term with occult
Materials and methods: A total of 40 patients at stage-I, who have undergone radical
inguinal orchiectomy intervention for testicular tumor between 2015 and 2019, and 43
control individuals without any testicular complaints were included in this retrospective
study. The relationship between pathological risk factors for occult metastatic disease in
Stage-I testicular cancer and NLR/PLR values were investigated.
Results: The average age was 30.05 years, and there was no significant difference
between the groups by means of age (p=0.150). The NLR and PLR values of the tumor
group were prominently higher in the patient group, when compared with the control
group (p=0.001 and p=0.016, respectively). In the correlation analysis between riskfactors for occult metastatic disease in Stage-I testicular cancer and NLR/PLR, we have
found that only a significant correlation was present in terms of tumor size.
Conclusion: As a result, we have concluded that NLR increases in all types of
testicular tumors. We suggest that higher NLR ratio values can be used as prognostic
marker in clinical practice.
Key words: Testicular tumor, occult metastasis, neutrophil/lymphocyte ratio,