The Predictive Value of Precise‑Dapt Score for Mortality in Patients with Acute Decompansed Heart Failure

Demir M., Korkmaz A., Demirtas B.

İnternational Journal of Cardiovascular Academy, vol.7, pp.70-77, 2021 (Peer-Reviewed Journal)

Abstract

Introduction: Acute decompensated heart failure (ADHF) is an emergency clinical syndrome defined as a sudden worsening of heart failure. PREdicting bleeding Complications In patients undergoing Stent implantation and subsEquent DualAnti‑Platelet Therapy (PRECISE‑DAPT) score is a new scoring used in the management of duration of dual‐antiplatelet therapy after coronary intervention.We presented the hypothesisthat this scoring can be used as a predictor of mortality in heart failure. Objective:In thisstudy, the correlation between mortality and PRECISE‑DAPT score will be analyzed in patients diagnosed withADHF. Materials and Methods: A total of 114 patients hospitalized with a diagnosis ofADHF were included in this study. The patients were divided into two groups: PRECISE‑DAPT score ≥25 and PRECISE‑DAPT score <25, and these groups were evaluated in terms of correlation with early (<6 months), late (>6 months) and overall mortality. Results: According to univariate analysis, it was found that PRECISE‑DAPT score was significantly related with early (P < 0.001), late (P < 0.001), and overall (P < 0.001) mortality. Multivariate Cox regression analysis showed that PRECISE‑DAPT was independently associated with late (hazard ratio: 6.6; 95% confidence interval [CI] 1.6–27.3; P = 0.009) and overall (hazard ratio: 11.3; 95% CI 3.2–40.9; P < 0.001) mortality. According to Kaplan– Meier curve, those with a score of ≥25 were shown to have significantly higher mortality. The predictive ability for the PRECISE‑DAPT score threshold value of 25 was investigated in 3 mortality subgroups. Conclusion: The PRECISE‑DAPT score may be a significant independent predictor of mortality in patients with ADHF. Limitations: This study is subject to the limitations inherent to a retrospective study and the sample size in our study is relatively small.