Effect of Hydrogen Sulfide on Kidney Injury in Rat Model of Crush Syndrome


Teksen Y. , Kadioglu E. , Kocak C., Kocak H.

JOURNAL OF SURGICAL RESEARCH, vol.235, pp.470-478, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 235
  • Publication Date: 2019
  • Doi Number: 10.1016/j.jss.2018.10.033
  • Title of Journal : JOURNAL OF SURGICAL RESEARCH
  • Page Numbers: pp.470-478

Abstract

Background: Acute kidney injury is the most serious complication of crush syndrome. Hydrogen sulfide (H2S) is an endogenously produced gaseous signaling molecule. It is involved in homeostatic functions, such as blood pressure control, apoptosis, oxidative stress, and inflammation. In this study, effects of H2S on kidney injury were investigated in a rat model of crush syndrome.