Effect of Hydrogen Sulfide on Kidney Injury in Rat Model of Crush Syndrome

Teksen Y., Kadioglu E., Kocak C., Kocak H.

JOURNAL OF SURGICAL RESEARCH, vol.235, pp.470-478, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 235
  • Publication Date: 2019
  • Doi Number: 10.1016/j.jss.2018.10.033
  • Journal Name: JOURNAL OF SURGICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.470-478
  • Kütahya Health Sciences University Affiliated: Yes

Abstract

Background: Acute kidney injury is the most serious complication of crush syndrome. Hydrogen sulfide (H2S) is an endogenously produced gaseous signaling molecule. It is involved in homeostatic functions, such as blood pressure control, apoptosis, oxidative stress, and inflammation. In this study, effects of H2S on kidney injury were investigated in a rat model of crush syndrome.