Effect of Hydrogen Sulfide on Kidney Injury in Rat Model of Crush Syndrome


Teksen Y. , Kadioglu E. , Kocak C., Kocak H.

JOURNAL OF SURGICAL RESEARCH, cilt.235, ss.470-478, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 235
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.jss.2018.10.033
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Sayfa Sayıları: ss.470-478

Özet

Background: Acute kidney injury is the most serious complication of crush syndrome. Hydrogen sulfide (H2S) is an endogenously produced gaseous signaling molecule. It is involved in homeostatic functions, such as blood pressure control, apoptosis, oxidative stress, and inflammation. In this study, effects of H2S on kidney injury were investigated in a rat model of crush syndrome.