© 2015 The Association for Perioperative Practice All legal and moral rights reserved.There is a mutual interaction between health and the workplace. Health affects the capacity to work and working conditions affect a worker's health. Operating rooms (ORs) are stressful, complex settings in which there are ergonomic risk factors, such as lifting/moving heavy equipment. Work-related musculoskeletal disorders (WRMSDs) can arise due to unhealthy ergonomic conditions. Our study showed that nurses had been absent from work and/or retired early due to WRMSDs. Good ergonomic conditions in ORs increase nurses' occupational health and safety, their job satisfaction and performance. These factors contribute to patient care outcomes in a positive way.